Introduction and application of 2-amino-5-nitrothiazole properties


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The 2-amino-5-nitrothiazole properties are a chemical with the formula C6H7N and molecular weight 93.126.

2-amino-5-nitrothiazole properties are homologous to pyridine, which is an aromatic and six-membered ring, similar to benzene in some respects, but different from benzene. For example, toluene has no isomer, There are three isomers of 2-amino-5-nitrothiazole properties, Namely, 2-2-amino-5-nitrothiazole properties[1], 3-2-amino-5-nitrothiazole properties[2] and 4-2-amino-5-nitrothiazole properties properties[3]. Its molecular weight is 93.13. It exists naturally in coal tar and has active chemical properties. It can react with side chain oxidation and nitrogen substitution, or condensation with aldehydes and ketones under alkali catalysis.

[1] Also known as alpha-2-amino -5-nitrothiazole properties, alpha-picoline. Colorless liquid. It has a strong pungent odor. Relative density 0.9462. Melting point -66.8℃. The boiling point is 128.8℃. Refractive index 1.4957. Flash point 26℃. Soluble in water and acetone, miscible with ethanol and ether. Composed of azeotrope with water, the content of this product is 52%, the boiling point is 93.5℃. Rat transoral LD501410 mg/kg.

Purpose: Raw material for the production of 2-vinylpyridine; Pesticide raw materials, production of "azoxadine", "pyridine-2, 5-dicarboxylate", "diphloridine", "chloridine", "dioxypicolinic acid", "methyliodide - 2-pyridinaldoxime", "toxatrazine" and so on.

[2] Also known as beta-2-amino -5-nitrothiazole properties, beta-picoline. Colorless and transparent liquid. It has a pungent odor. The taste is slightly sweet. The relative densities are 0.9560 and 0.9613(15℃). Melting point -18.3℃. Boiling point 143.9℃. Refractive index 1.5403. Flash point 36℃(closed). Miscible with water, ethanol and ether. This product is composed of azeotrope with water. The content of this product is 27% and the eutectic point is 96.7℃. Unlike [1] and [3], this product has poor methyl reactivity. Has a stimulating effect on the skin, can also be absorbed through the skin, its vapor stimulates the eyes and respiratory tract, cause inflammation, serious cause blisters, vomiting, headache and other symptoms. Rat transoral LD50790mg/kg.

Uses: pesticide raw materials, the production of herbicides, insecticides, fungicides, such as "protonicotinoid", "benzopyriol" and rodenticide "antirhamine"; Food additive: 2-2-amino-5-nitrothiazole properties are added when meat products are processed, which can combine with myoglobin to prevent oxidation and keep the color of meat fresh. When [2] is added to bread, pastries, rice products, dairy products, ham, sausage and other foods, it can play the role of vitamin strengthening medicine, and can be used instead of vitamin B. As a vitamin fortification agent can be added to infant milk powder, women's pregnancy milk powder, food and drink; It can also be used as medicine to treat niacin deficiency; Feed additive; Producing niacinamide or replacing it; Alcohol modifier; Dye intermediate; Rubber vulcanizing agent and film sensitizer raw materials, etc.

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